Functional significance of U2AF1 S34F mutations in lung adenocarcinomas
Functional significance of U2AF1 S34F mutations in lung adenocarcinomas
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The functional role of U2AF1 mutations in lung adenocarcinomas (LUADs) remains incompletely understood. Here, we report a significant co-occurrence of U2AF1 S34F mutations with ROS1 translocations in LUADs. To characterize this interaction, we profiled effects of S34F on the transcriptome-wide distribution of RNA binding and alternative splicing in...
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Functional significance of U2AF1 S34F mutations in lung adenocarcinomas
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TN_cdi_doaj_primary_oai_doaj_org_article_0437a662c77043ed87f4f0be71eb3a88
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0437a662c77043ed87f4f0be71eb3a88
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-13392-y
