Autophagy-mediated occludin degradation contributes to blood-brain barrier disruption during ischemi...
Autophagy-mediated occludin degradation contributes to blood-brain barrier disruption during ischemia in bEnd.3 brain endothelial cells and rat ischemic stroke models
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England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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The blood-brain barrier (BBB) maintains homeostasis of the brain environment by tightly regulating the entry of substances from systemic circulation. A breach in the BBB results in increased permeability to potentially toxic substances and is an important contributor to amplification of ischemic brain damage. The precise molecular pathways that res...
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Autophagy-mediated occludin degradation contributes to blood-brain barrier disruption during ischemia in bEnd.3 brain endothelial cells and rat ischemic stroke models
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TN_cdi_doaj_primary_oai_doaj_org_article_0447bbe0404c4146a9f179c77d21fb8b
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0447bbe0404c4146a9f179c77d21fb8b
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ISSN
2045-8118
E-ISSN
2045-8118
DOI
10.1186/s12987-020-00182-8