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Autophagy-mediated occludin degradation contributes to blood-brain barrier disruption during ischemi...

Autophagy-mediated occludin degradation contributes to blood-brain barrier disruption during ischemi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0447bbe0404c4146a9f179c77d21fb8b

Autophagy-mediated occludin degradation contributes to blood-brain barrier disruption during ischemia in bEnd.3 brain endothelial cells and rat ischemic stroke models

About this item

Full title

Autophagy-mediated occludin degradation contributes to blood-brain barrier disruption during ischemia in bEnd.3 brain endothelial cells and rat ischemic stroke models

Publisher

England: BioMed Central Ltd

Journal title

Fluids and barriers of the CNS, 2020-03, Vol.17 (1), p.21-12, Article 21

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

The blood-brain barrier (BBB) maintains homeostasis of the brain environment by tightly regulating the entry of substances from systemic circulation. A breach in the BBB results in increased permeability to potentially toxic substances and is an important contributor to amplification of ischemic brain damage. The precise molecular pathways that res...

Alternative Titles

Full title

Autophagy-mediated occludin degradation contributes to blood-brain barrier disruption during ischemia in bEnd.3 brain endothelial cells and rat ischemic stroke models

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_0447bbe0404c4146a9f179c77d21fb8b

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0447bbe0404c4146a9f179c77d21fb8b

Other Identifiers

ISSN

2045-8118

E-ISSN

2045-8118

DOI

10.1186/s12987-020-00182-8

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