Cellular sequestrases maintain basal Hsp70 capacity ensuring balanced proteostasis
Cellular sequestrases maintain basal Hsp70 capacity ensuring balanced proteostasis
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Maintenance of cellular proteostasis is achieved by a multi-layered quality control network, which counteracts the accumulation of misfolded proteins by refolding and degradation pathways. The organized sequestration of misfolded proteins, actively promoted by cellular sequestrases, represents a third strategy of quality control. Here we determine...
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Cellular sequestrases maintain basal Hsp70 capacity ensuring balanced proteostasis
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TN_cdi_doaj_primary_oai_doaj_org_article_046a4baa20df4aac872c48bb40ab57d6
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_046a4baa20df4aac872c48bb40ab57d6
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-12868-1
