Feasibility of predicting allele specific expression from DNA sequencing using machine learning
Feasibility of predicting allele specific expression from DNA sequencing using machine learning
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Publisher
London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Allele specific expression (ASE) concerns divergent expression quantity of alternative alleles and is measured by RNA sequencing. Multiple studies show that ASE plays a role in hereditary diseases by modulating penetrance or phenotype severity. However, genome diagnostics is based on DNA sequencing and therefore neglects gene expression regulation...
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Full title
Feasibility of predicting allele specific expression from DNA sequencing using machine learning
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TN_cdi_doaj_primary_oai_doaj_org_article_046bc28e1cc24a58a64d6f222d461d04
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_046bc28e1cc24a58a64d6f222d461d04
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-021-89904-y
