Subtype heterogeneity and epigenetic convergence in neuroendocrine prostate cancer
Subtype heterogeneity and epigenetic convergence in neuroendocrine prostate cancer
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Author / Creator
Cejas, Paloma , Xie, Yingtian , Font-Tello, Alba , Lim, Klothilda , Syamala, Sudeepa , Qiu, Xintao , Tewari, Alok K. , Shah, Neel , Nguyen, Holly M. , Patel, Radhika A. , Brown, Lisha , Coleman, Ilsa , Hackeng, Wenzel M. , Brosens, Lodewijk , Dreijerink, Koen M. A. , Ellis, Leigh , Alaiwi, Sarah Abou , Seo, Ji-Heui , Baca, Sylvan , Beltran, Himisha , Khani, Francesca , Pomerantz, Mark , Dall’Agnese, Alessandra , Crowdis, Jett , Van Allen, Eliezer M. , Bellmunt, Joaquim , Morrisey, Colm , Nelson, Peter S. , DeCaprio, James , Farago, Anna , Dyson, Nicholas , Drapkin, Benjamin , Liu, X. Shirley , Freedman, Matthew , Haffner, Michael C. , Corey, Eva , Brown, Myles and Long, Henry W.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Neuroendocrine carcinomas (NEC) are tumors expressing markers of neuronal differentiation that can arise at different anatomic sites but have strong histological and clinical similarities. Here we report the chromatin landscapes of a range of human NECs and show convergence to the activation of a common epigenetic program. With a particular focus o...
Alternative Titles
Full title
Subtype heterogeneity and epigenetic convergence in neuroendocrine prostate cancer
Authors, Artists and Contributors
Author / Creator
Xie, Yingtian
Font-Tello, Alba
Lim, Klothilda
Syamala, Sudeepa
Qiu, Xintao
Tewari, Alok K.
Shah, Neel
Nguyen, Holly M.
Patel, Radhika A.
Brown, Lisha
Coleman, Ilsa
Hackeng, Wenzel M.
Brosens, Lodewijk
Dreijerink, Koen M. A.
Ellis, Leigh
Alaiwi, Sarah Abou
Seo, Ji-Heui
Baca, Sylvan
Beltran, Himisha
Khani, Francesca
Pomerantz, Mark
Dall’Agnese, Alessandra
Crowdis, Jett
Van Allen, Eliezer M.
Bellmunt, Joaquim
Morrisey, Colm
Nelson, Peter S.
DeCaprio, James
Farago, Anna
Dyson, Nicholas
Drapkin, Benjamin
Liu, X. Shirley
Freedman, Matthew
Haffner, Michael C.
Corey, Eva
Brown, Myles
Long, Henry W.
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_049dc4c6a6fd4e8a9fc4ad8f4f885b4e
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_049dc4c6a6fd4e8a9fc4ad8f4f885b4e
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-26042-z