Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM
Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM
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Author / Creator
Antanasijevic, Aleksandar , Sewall, Leigh M. , Cottrell, Christopher A. , Carnathan, Diane G. , Jimenez, Luis E. , Ngo, Julia T. , Silverman, Jennifer B. , Groschel, Bettina , Georgeson, Erik , Bhiman, Jinal , Bastidas, Raiza , LaBranche, Celia , Allen, Joel D. , Copps, Jeffrey , Perrett, Hailee R. , Rantalainen, Kimmo , Cannac, Fabien , Yang, Yuhe R. , de la Peña, Alba Torrents , Rocha, Rebeca Froes , Berndsen, Zachary T. , Baker, David , King, Neil P. , Sanders, Rogier W. , Moore, John P. , Crotty, Shane , Crispin, Max , Montefiori, David C. , Burton, Dennis R. , Schief, William R. , Silvestri, Guido and Ward, Andrew B.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Engineered ectodomain trimer immunogens based on BG505 envelope glycoprotein are widely utilized as components of HIV vaccine development platforms. In this study, we used rhesus macaques to evaluate the immunogenicity of several stabilized BG505 SOSIP constructs both as free trimers and presented on a nanoparticle. We applied a cryoEM-based method...
Alternative Titles
Full title
Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM
Authors, Artists and Contributors
Author / Creator
Sewall, Leigh M.
Cottrell, Christopher A.
Carnathan, Diane G.
Jimenez, Luis E.
Ngo, Julia T.
Silverman, Jennifer B.
Groschel, Bettina
Georgeson, Erik
Bhiman, Jinal
Bastidas, Raiza
LaBranche, Celia
Allen, Joel D.
Copps, Jeffrey
Perrett, Hailee R.
Rantalainen, Kimmo
Cannac, Fabien
Yang, Yuhe R.
de la Peña, Alba Torrents
Rocha, Rebeca Froes
Berndsen, Zachary T.
Baker, David
King, Neil P.
Sanders, Rogier W.
Moore, John P.
Crotty, Shane
Crispin, Max
Montefiori, David C.
Burton, Dennis R.
Schief, William R.
Silvestri, Guido
Ward, Andrew B.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_04ab87746dbe4d4ea81ab039e453c3ac
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_04ab87746dbe4d4ea81ab039e453c3ac
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-25087-4
