Stage-resolved Hi-C analyses reveal meiotic chromosome organizational features influencing homolog a...
Stage-resolved Hi-C analyses reveal meiotic chromosome organizational features influencing homolog alignment
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Author / Creator
Zuo, Wu , Chen, Guangming , Gao, Zhimei , Li, Shuai , Chen, Yanyan , Huang, Chenhui , Chen, Juan , Chen, Zhengjun , Lei, Ming and Bian, Qian
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
During meiosis, chromosomes exhibit dramatic changes in morphology and intranuclear positioning. How these changes influence homolog pairing, alignment, and recombination remain elusive. Using Hi-C, we systematically mapped 3D genome architecture throughout all meiotic prophase substages during mouse spermatogenesis. Our data uncover two major chro...
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Full title
Stage-resolved Hi-C analyses reveal meiotic chromosome organizational features influencing homolog alignment
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_04bab0aa74074e349ddf98974f462098
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_04bab0aa74074e349ddf98974f462098
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-26033-0