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Remodeling of secretory lysosomes during education tunes functional potential in NK cells

Remodeling of secretory lysosomes during education tunes functional potential in NK cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_05087ace24334bc9a23a8959b77fbf46

Remodeling of secretory lysosomes during education tunes functional potential in NK cells

About this item

Full title

Remodeling of secretory lysosomes during education tunes functional potential in NK cells

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2019-01, Vol.10 (1), p.514-514, Article 514

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Inhibitory signaling during natural killer (NK) cell education translates into increased responsiveness to activation; however, the intracellular mechanism for functional tuning by inhibitory receptors remains unclear. Secretory lysosomes are part of the acidic lysosomal compartment that mediates intracellular signalling in several cell types. Here...

Alternative Titles

Full title

Remodeling of secretory lysosomes during education tunes functional potential in NK cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_05087ace24334bc9a23a8959b77fbf46

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_05087ace24334bc9a23a8959b77fbf46

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-019-08384-x

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