Antibiotic polymyxin arranges lipopolysaccharide into crystalline structures to solidify the bacteri...
Antibiotic polymyxin arranges lipopolysaccharide into crystalline structures to solidify the bacterial membrane
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Polymyxins are last-resort antibiotics with potent activity against multi-drug resistant pathogens. They interact with lipopolysaccharide (LPS) in bacterial membranes, but mechanistic details at the molecular level remain unclear. Here, we characterize the interaction of polymyxins with native, LPS-containing outer membrane patches of
Escherichi...
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Full title
Antibiotic polymyxin arranges lipopolysaccharide into crystalline structures to solidify the bacterial membrane
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TN_cdi_doaj_primary_oai_doaj_org_article_0539de9771d743a08fee0604262fc708
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0539de9771d743a08fee0604262fc708
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-33838-0
