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The co-treatment of rosuvastatin with dapagliflozin synergistically inhibited apoptosis via activati...

The co-treatment of rosuvastatin with dapagliflozin synergistically inhibited apoptosis via activati...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0569fe67ae6d45359ff50cf2dbfafd14

The co-treatment of rosuvastatin with dapagliflozin synergistically inhibited apoptosis via activating the PI3K/AKt/mTOR signaling pathway in myocardial ischemia/reperfusion injury rats

About this item

Full title

The co-treatment of rosuvastatin with dapagliflozin synergistically inhibited apoptosis via activating the PI3K/AKt/mTOR signaling pathway in myocardial ischemia/reperfusion injury rats

Publisher

Poland: De Gruyter

Journal title

Open medicine (Warsaw, Poland), 2021-01, Vol.15 (1), p.047-057

Language

English

Formats

Publication information

Publisher

Poland: De Gruyter

More information

Scope and Contents

Contents

The purpose of the present study was to evaluate the role of co-treatment of rosuvastatin (RSV) and dapagliflozin (DGZ) preconditioning in myocardium ischemia/reperfusion (I/R) injury and to further investigate the underlying mechanism.
Sprague-Dawley (SD) rats (
= 25) were divided into five groups randomly: (1) Sham, (2) I/R, (3) I/R + RSV (...

Alternative Titles

Full title

The co-treatment of rosuvastatin with dapagliflozin synergistically inhibited apoptosis via activating the PI3K/AKt/mTOR signaling pathway in myocardial ischemia/reperfusion injury rats

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_0569fe67ae6d45359ff50cf2dbfafd14

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0569fe67ae6d45359ff50cf2dbfafd14

Other Identifiers

ISSN

2391-5463

E-ISSN

2391-5463

DOI

10.1515/med-2021-0005

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