The co-treatment of rosuvastatin with dapagliflozin synergistically inhibited apoptosis via activati...
The co-treatment of rosuvastatin with dapagliflozin synergistically inhibited apoptosis via activating the PI3K/AKt/mTOR signaling pathway in myocardial ischemia/reperfusion injury rats
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Author / Creator
Gong, Lei , Wang, Xuyang , Pan, Jinyu , Zhang, Mingjun , Liu, Dian , Liu, Ming , Li, Li and An, Fengshuang
Publisher
Poland: De Gruyter
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Language
English
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Publisher
Poland: De Gruyter
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Contents
The purpose of the present study was to evaluate the role of co-treatment of rosuvastatin (RSV) and dapagliflozin (DGZ) preconditioning in myocardium ischemia/reperfusion (I/R) injury and to further investigate the underlying mechanism.
Sprague-Dawley (SD) rats (
= 25) were divided into five groups randomly: (1) Sham, (2) I/R, (3) I/R + RSV (...
Alternative Titles
Full title
The co-treatment of rosuvastatin with dapagliflozin synergistically inhibited apoptosis via activating the PI3K/AKt/mTOR signaling pathway in myocardial ischemia/reperfusion injury rats
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_0569fe67ae6d45359ff50cf2dbfafd14
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0569fe67ae6d45359ff50cf2dbfafd14
Other Identifiers
ISSN
2391-5463
E-ISSN
2391-5463
DOI
10.1515/med-2021-0005