Sulphostin-inspired N-phosphonopiperidones as selective covalent DPP8 and DPP9 inhibitors
Sulphostin-inspired N-phosphonopiperidones as selective covalent DPP8 and DPP9 inhibitors
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Covalent chemical probes and drugs combine unique pharmacologic properties with the availability of straightforward compound profiling technologies via chemoproteomic platforms. These advantages have fostered the development of suitable electrophilic “warheads” for systematic covalent chemical probe discovery. Despite undisputable advances in the l...
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Sulphostin-inspired N-phosphonopiperidones as selective covalent DPP8 and DPP9 inhibitors
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TN_cdi_doaj_primary_oai_doaj_org_article_057944e2b2ef4e908ddde71633d1c107
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_057944e2b2ef4e908ddde71633d1c107
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-025-58493-z
