Mesothelioma-associated fibroblasts enhance proliferation and migration of pleural mesothelioma cell...
Mesothelioma-associated fibroblasts enhance proliferation and migration of pleural mesothelioma cells via c-Met/PI3K and WNT signaling but do not protect against cisplatin
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Author / Creator
Ries, Alexander , Flehberger, Daniela , Slany, Astrid , Pirker, Christine , Mader, Johanna C. , Mohr, Thomas , Schelch, Karin , Sinn, Katharina , Mosleh, Berta , Hoda, Mir Alireza , Dome, Balazs , Dolznig, Helmut , Krupitza, Georg , Müllauer, Leonhard , Gerner, Christopher , Berger, Walter and Grusch, Michael
Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Pleural mesothelioma (PM) is an aggressive malignancy with poor prognosis. Unlike many other cancers, PM is mostly characterized by inactivation of tumor suppressor genes. Its highly malignant nature in absence of tumor driving oncogene mutations indicates an extrinsic supply of stimulating signals by cells of the tumor microenvironment (TME). Canc...
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Full title
Mesothelioma-associated fibroblasts enhance proliferation and migration of pleural mesothelioma cells via c-Met/PI3K and WNT signaling but do not protect against cisplatin
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TN_cdi_doaj_primary_oai_doaj_org_article_0584feb1baa7455e98b30e32f6b10aef
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0584feb1baa7455e98b30e32f6b10aef
Other Identifiers
ISSN
1756-9966,0392-9078
E-ISSN
1756-9966
DOI
10.1186/s13046-022-02582-0
