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Hypersensitivity of myelinated A-fibers via toll-like receptor 5 promotes mechanical allodynia in te...

Hypersensitivity of myelinated A-fibers via toll-like receptor 5 promotes mechanical allodynia in te...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_05ac6b7462934fa48b269f7704dd23bf

Hypersensitivity of myelinated A-fibers via toll-like receptor 5 promotes mechanical allodynia in tenascin-X-deficient mice associated with Ehlers–Danlos syndrome

About this item

Full title

Hypersensitivity of myelinated A-fibers via toll-like receptor 5 promotes mechanical allodynia in tenascin-X-deficient mice associated with Ehlers–Danlos syndrome

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2023-10, Vol.13 (1), p.18490-18490, Article 18490

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Deficiency of an extracellular matrix glycoprotein tenascin-X (TNX) leads to a human heritable disorder Ehlers–Danlos syndrome, and TNX-deficient patients complain of chronic joint pain, myalgia, paresthesia, and axonal polyneuropathy. We previously reported that TNX-deficient (
Tnxb
−/

) mice exhibit mechanical allodynia and hypersen...

Alternative Titles

Full title

Hypersensitivity of myelinated A-fibers via toll-like receptor 5 promotes mechanical allodynia in tenascin-X-deficient mice associated with Ehlers–Danlos syndrome

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_05ac6b7462934fa48b269f7704dd23bf

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_05ac6b7462934fa48b269f7704dd23bf

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-023-45638-7

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