R-loop proximity proteomics identifies a role of DDX41 in transcription-associated genomic instabili...
R-loop proximity proteomics identifies a role of DDX41 in transcription-associated genomic instability
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Transcription poses a threat to genomic stability through the formation of R-loops that can obstruct progression of replication forks. R-loops are three-stranded nucleic acid structures formed by an RNA–DNA hybrid with a displaced non-template DNA strand. We developed RNA–DNA Proximity Proteomics to map the R-loop proximal proteome of human cells u...
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R-loop proximity proteomics identifies a role of DDX41 in transcription-associated genomic instability
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TN_cdi_doaj_primary_oai_doaj_org_article_05bb324df10645da96b7973878aa788d
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_05bb324df10645da96b7973878aa788d
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-27530-y
