Hypothalamic leptin action is mediated by histone deacetylase 5
Hypothalamic leptin action is mediated by histone deacetylase 5
About this item
Full title
Author / Creator
Kabra, Dhiraj G. , Pfuhlmann, Katrin , García-Cáceres, Cristina , Schriever, Sonja C. , Casquero García, Veronica , Kebede, Adam Fiseha , Fuente-Martin, Esther , Trivedi, Chitrang , Heppner, Kristy , Uhlenhaut, N. Henriette , Legutko, Beata , Kabra, Uma D. , Gao, Yuanqing , Yi, Chun-Xia , Quarta, Carmelo , Clemmensen, Christoffer , Finan, Brian , Müller, Timo D. , Meyer, Carola W. , Paez-Pereda, Marcelo , Stemmer, Kerstin , Woods, Stephen C. , Perez-Tilve, Diego , Schneider, Robert , Olson, Eric N. , Tschöp, Matthias H. and Pfluger, Paul T.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Hypothalamic leptin signalling has a key role in food intake and energy-balance control and is often impaired in obese individuals. Here we identify histone deacetylase 5 (HDAC5) as a regulator of leptin signalling and organismal energy balance. Global HDAC5 KO mice have increased food intake and greater diet-induced obesity when fed high-fat diet....
Alternative Titles
Full title
Hypothalamic leptin action is mediated by histone deacetylase 5
Authors, Artists and Contributors
Author / Creator
Pfuhlmann, Katrin
García-Cáceres, Cristina
Schriever, Sonja C.
Casquero García, Veronica
Kebede, Adam Fiseha
Fuente-Martin, Esther
Trivedi, Chitrang
Heppner, Kristy
Uhlenhaut, N. Henriette
Legutko, Beata
Kabra, Uma D.
Gao, Yuanqing
Yi, Chun-Xia
Quarta, Carmelo
Clemmensen, Christoffer
Finan, Brian
Müller, Timo D.
Meyer, Carola W.
Paez-Pereda, Marcelo
Stemmer, Kerstin
Woods, Stephen C.
Perez-Tilve, Diego
Schneider, Robert
Olson, Eric N.
Tschöp, Matthias H.
Pfluger, Paul T.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_05d180e6a43443a4a0aaf1a16b919fe2
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_05d180e6a43443a4a0aaf1a16b919fe2
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms10782
