Selection of nanobodies with broad neutralizing potential against primary HIV-1 strains using solubl...
Selection of nanobodies with broad neutralizing potential against primary HIV-1 strains using soluble subtype C gp140 envelope trimers
About this item
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Author / Creator
Koch, Kathrin , Kalusche, Sarah , Torres, Jonathan L. , Stanfield, Robyn L. , Danquah, Welbeck , Khazanehdari, Kamal , von Briesen, Hagen , Geertsma, Eric R. , Wilson, Ian A. , Wernery, Ulrich , Koch-Nolte, Friedrich , Ward, Andrew B. , Dietrich, Ursula and SLAC National Accelerator Laboratory (SLAC), Menlo Park, CA (United States). Stanford Synchrotron Radiation Lightsource (SSRL)
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Broadly neutralizing antibodies (bnAbs) against HIV-1 protect from infection and reduce viral load upon therapeutic applications. However no vaccine was able so far to induce bnAbs demanding their expensive biotechnological production. For clinical applications, nanobodies (VHH) derived from heavy chain only antibodies from
Camelidae
, may be...
Alternative Titles
Full title
Selection of nanobodies with broad neutralizing potential against primary HIV-1 strains using soluble subtype C gp140 envelope trimers
Authors, Artists and Contributors
Author / Creator
Kalusche, Sarah
Torres, Jonathan L.
Stanfield, Robyn L.
Danquah, Welbeck
Khazanehdari, Kamal
von Briesen, Hagen
Geertsma, Eric R.
Wilson, Ian A.
Wernery, Ulrich
Koch-Nolte, Friedrich
Ward, Andrew B.
Dietrich, Ursula
SLAC National Accelerator Laboratory (SLAC), Menlo Park, CA (United States). Stanford Synchrotron Radiation Lightsource (SSRL)
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_065cbec988884c7d94a11dd65043ca0e
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_065cbec988884c7d94a11dd65043ca0e
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-017-08273-7