Identifying chemogenetic interactions from CRISPR screens with drugZ
Identifying chemogenetic interactions from CRISPR screens with drugZ
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Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Chemogenetic profiling enables the identification of gene mutations that enhance or suppress the activity of chemical compounds. This knowledge provides insights into drug mechanism of action, genetic vulnerabilities, and resistance mechanisms, all of which may help stratify patient populations and improve drug efficacy. CRISPR-based screening enab...
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Full title
Identifying chemogenetic interactions from CRISPR screens with drugZ
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TN_cdi_doaj_primary_oai_doaj_org_article_0660691297e4473f951c2f4ee9ed5f00
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0660691297e4473f951c2f4ee9ed5f00
Other Identifiers
ISSN
1756-994X
E-ISSN
1756-994X
DOI
10.1186/s13073-019-0665-3
