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From Genetic Alterations to Tumor Microenvironment: The Ariadne’s String in Pancreatic Cancer

From Genetic Alterations to Tumor Microenvironment: The Ariadne’s String in Pancreatic Cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_06891359fa144ed89c24fb7e14fc01d5

From Genetic Alterations to Tumor Microenvironment: The Ariadne’s String in Pancreatic Cancer

About this item

Full title

From Genetic Alterations to Tumor Microenvironment: The Ariadne’s String in Pancreatic Cancer

Publisher

Switzerland: MDPI

Journal title

Cells (Basel, Switzerland), 2020-01, Vol.9 (2), p.309

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI

More information

Scope and Contents

Contents

The threatening notoriety of pancreatic cancer mainly arises from its negligible early diagnosis, highly aggressive progression, failure of conventional therapeutic options and consequent very poor prognosis. The most important driver genes of pancreatic cancer are the oncogene KRAS and the tumor suppressors TP53, CDKN2A, and SMAD4. Although the pr...

Alternative Titles

Full title

From Genetic Alterations to Tumor Microenvironment: The Ariadne’s String in Pancreatic Cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_06891359fa144ed89c24fb7e14fc01d5

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_06891359fa144ed89c24fb7e14fc01d5

Other Identifiers

ISSN

2073-4409

E-ISSN

2073-4409

DOI

10.3390/cells9020309

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