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Generation of a Vero-Based Packaging Cell Line to Produce SV40 Gene Delivery Vectors for Use in Clin...

Generation of a Vero-Based Packaging Cell Line to Produce SV40 Gene Delivery Vectors for Use in Clin...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_06c68bd3b6a94f5094f1b73b60f6b041

Generation of a Vero-Based Packaging Cell Line to Produce SV40 Gene Delivery Vectors for Use in Clinical Gene Therapy Studies

About this item

Full title

Generation of a Vero-Based Packaging Cell Line to Produce SV40 Gene Delivery Vectors for Use in Clinical Gene Therapy Studies

Publisher

United States: Elsevier Limited

Journal title

Molecular therapy. Methods & clinical development, 2017-09, Vol.6 (C), p.124-134

Language

English

Formats

Publication information

Publisher

United States: Elsevier Limited

More information

Scope and Contents

Contents

Replication-defective (RD) recombinant simian virus 40 (SV40)-based gene delivery vectors hold a great potential for clinical applications because of their presumed non-immunogenicity and capacity to induce immune tolerance to the transgene products in humans. However, the clinical use of SV40 vectors has been hampered by the lack of a packaging ce...

Alternative Titles

Full title

Generation of a Vero-Based Packaging Cell Line to Produce SV40 Gene Delivery Vectors for Use in Clinical Gene Therapy Studies

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_06c68bd3b6a94f5094f1b73b60f6b041

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_06c68bd3b6a94f5094f1b73b60f6b041

Other Identifiers

ISSN

2329-0501

E-ISSN

2329-0501

DOI

10.1016/j.omtm.2017.06.007

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