High fat diet ameliorates mitochondrial cardiomyopathy in CHCHD10 mutant mice
High fat diet ameliorates mitochondrial cardiomyopathy in CHCHD10 mutant mice
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Mutations in
CHCHD10
, a mitochondrial protein with undefined functions, are associated with autosomal dominant mitochondrial diseases.
Chchd10
knock-in mice harboring a heterozygous S55L mutation (equivalent to human pathogenic S59L) develop a fatal mitochondrial cardiomyopathy caused by CHCHD10 aggregation and proteotoxic mitochondria...
Alternative Titles
Full title
High fat diet ameliorates mitochondrial cardiomyopathy in CHCHD10 mutant mice
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TN_cdi_doaj_primary_oai_doaj_org_article_06da78e884b74bbabfb6411ca3018288
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_06da78e884b74bbabfb6411ca3018288
Other Identifiers
ISSN
1757-4684,1757-4676
E-ISSN
1757-4684
DOI
10.1038/s44321-024-00067-5
