Exome sequencing revealed comparable frequencies of RNF43 and BRAF mutations in Middle Eastern color...
Exome sequencing revealed comparable frequencies of RNF43 and BRAF mutations in Middle Eastern colorectal cancer
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Mutation-induced activation of
Wnt
-β Catenin signaling pathway is frequent in CRC. The E3 ubiquitin ligase,
RNF43
, has been reported to negatively regulate the
Wnt
signaling pathway and
RNF43
mutations are frequently seen in CRC. However, its role in Middle Eastern CRC remains unclear. Therefore, we employed Exome and Sang...
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Full title
Exome sequencing revealed comparable frequencies of RNF43 and BRAF mutations in Middle Eastern colorectal cancer
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TN_cdi_doaj_primary_oai_doaj_org_article_06f51a9eb5564d77b1bf7d21f9214529
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_06f51a9eb5564d77b1bf7d21f9214529
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-022-17449-9
