Involvement of Cyclooxygenase-2 in Establishing an Immunosuppressive Microenvironment in Tumorsphere...
Involvement of Cyclooxygenase-2 in Establishing an Immunosuppressive Microenvironment in Tumorspheres Derived from TMZ-Resistant Glioblastoma Cell Lines and Primary Cultures
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Switzerland: MDPI AG
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English
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Switzerland: MDPI AG
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Glioblastoma (GBM) is characterized by an immunosuppressive tumor microenvironment (TME) strictly associated with therapy resistance. Cyclooxygenase-2 (COX-2) fuels GBM proliferation, stemness, and chemoresistance. We previously reported that COX-2 upregulation induced by temozolomide (TMZ) supported chemoresistance. Also, COX-2 transfer by extrace...
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Involvement of Cyclooxygenase-2 in Establishing an Immunosuppressive Microenvironment in Tumorspheres Derived from TMZ-Resistant Glioblastoma Cell Lines and Primary Cultures
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TN_cdi_doaj_primary_oai_doaj_org_article_0708e706dec749d282408a7d15f5bbe8
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0708e706dec749d282408a7d15f5bbe8
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ISSN
2073-4409
E-ISSN
2073-4409
DOI
10.3390/cells13030258
