Challenging interpretation of germline TP53 variants based on the experience of a national comprehen...
Challenging interpretation of germline TP53 variants based on the experience of a national comprehensive cancer centre
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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TP53
variant interpretation is still challenging, especially in patients with attenuated Li–Fraumeni syndrome (LFS). We investigated the prevalence of pathogenic/likely pathogenic (P/LP) variants and LFS disease in the Hungarian population of cancer patients. By testing 893 patients with multiplex or familial cancer, we identified and functional...
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Challenging interpretation of germline TP53 variants based on the experience of a national comprehensive cancer centre
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TN_cdi_doaj_primary_oai_doaj_org_article_0714ce041823455f9c1ba4a58dc89331
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0714ce041823455f9c1ba4a58dc89331
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-023-41481-y
