Single-cell multi-omics reveals dyssynchrony of the innate and adaptive immune system in progressive...
Single-cell multi-omics reveals dyssynchrony of the innate and adaptive immune system in progressive COVID-19
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Author / Creator
Unterman, Avraham , Sumida, Tomokazu S. , Nouri, Nima , Yan, Xiting , Zhao, Amy Y. , Gasque, Victor , Schupp, Jonas C. , Asashima, Hiromitsu , Liu, Yunqing , Cosme, Carlos , Deng, Wenxuan , Chen, Ming , Raredon, Micha Sam Brickman , Hoehn, Kenneth B. , Wang, Guilin , Wang, Zuoheng , DeIuliis, Giuseppe , Ravindra, Neal G. , Li, Ningshan , Castaldi, Christopher , Wong, Patrick , Fournier, John , Bermejo, Santos , Sharma, Lokesh , Casanovas-Massana, Arnau , Vogels, Chantal B. F. , Wyllie, Anne L. , Grubaugh, Nathan D. , Melillo, Anthony , Meng, Hailong , Stein, Yan , Minasyan, Maksym , Mohanty, Subhasis , Ruff, William E. , Cohen, Inessa , Raddassi, Khadir , Niklason, Laura E. , Ko, Albert I. , Montgomery, Ruth R. , Farhadian, Shelli F. , Iwasaki, Akiko , Shaw, Albert C. , van Dijk, David , Zhao, Hongyu , Kleinstein, Steven H. , Hafler, David A. , Kaminski, Naftali , Dela Cruz, Charles S. , Yale IMPACT Research Team and The Yale IMPACT Research Team
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Dysregulated immune responses against the SARS-CoV-2 virus are instrumental in severe COVID-19. However, the immune signatures associated with immunopathology are poorly understood. Here we use multi-omics single-cell analysis to probe the dynamic immune responses in hospitalized patients with stable or progressive course of COVID-19, explore V(D)J...
Alternative Titles
Full title
Single-cell multi-omics reveals dyssynchrony of the innate and adaptive immune system in progressive COVID-19
Authors, Artists and Contributors
Author / Creator
Sumida, Tomokazu S.
Nouri, Nima
Yan, Xiting
Zhao, Amy Y.
Gasque, Victor
Schupp, Jonas C.
Asashima, Hiromitsu
Liu, Yunqing
Cosme, Carlos
Deng, Wenxuan
Chen, Ming
Raredon, Micha Sam Brickman
Hoehn, Kenneth B.
Wang, Guilin
Wang, Zuoheng
DeIuliis, Giuseppe
Ravindra, Neal G.
Li, Ningshan
Castaldi, Christopher
Wong, Patrick
Fournier, John
Bermejo, Santos
Sharma, Lokesh
Casanovas-Massana, Arnau
Vogels, Chantal B. F.
Wyllie, Anne L.
Grubaugh, Nathan D.
Melillo, Anthony
Meng, Hailong
Stein, Yan
Minasyan, Maksym
Mohanty, Subhasis
Ruff, William E.
Cohen, Inessa
Raddassi, Khadir
Niklason, Laura E.
Ko, Albert I.
Montgomery, Ruth R.
Farhadian, Shelli F.
Iwasaki, Akiko
Shaw, Albert C.
van Dijk, David
Zhao, Hongyu
Kleinstein, Steven H.
Hafler, David A.
Kaminski, Naftali
Dela Cruz, Charles S.
Yale IMPACT Research Team
The Yale IMPACT Research Team
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_071dfec07b41418ab54ed9c36dc0d83e
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_071dfec07b41418ab54ed9c36dc0d83e
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-27716-4
