Helicobacter pylori CagA promotes epithelial mesenchymal transition in gastric carcinogenesis via tr...
Helicobacter pylori CagA promotes epithelial mesenchymal transition in gastric carcinogenesis via triggering oncogenic YAP pathway
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Author / Creator
Li, Nianshuang , Feng, Yan , Hu, Yi , He, Cong , Xie, Chuan , Ouyang, Yaobin , Artim, Stephen C. , Huang, Deqiang , Zhu, Yin , Luo, Zhijun , Ge, Zhongming and Lu, Nonghua
Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Helicobacter pylori (H. pylori) delivers oncoprotein CagA into gastric epithelial cells via the T4SS and drives activation of multiple oncogenic signalling pathways. YAP, a core effector of the Hippo tumour suppressor pathway, is frequently overexpressed in human cancers, suggesting its potential tumor-promoting role. Although CagA is a casual fact...
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Full title
Helicobacter pylori CagA promotes epithelial mesenchymal transition in gastric carcinogenesis via triggering oncogenic YAP pathway
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_07633e0300954ab4a42d42c578fe69f0
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_07633e0300954ab4a42d42c578fe69f0
Other Identifiers
ISSN
1756-9966,0392-9078
E-ISSN
1756-9966
DOI
10.1186/s13046-018-0962-5
