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miR-181a initiates and perpetuates oncogenic transformation through the regulation of innate immune...

miR-181a initiates and perpetuates oncogenic transformation through the regulation of innate immune...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0767a885d74b4bc6bb838ba3fa5b0523

miR-181a initiates and perpetuates oncogenic transformation through the regulation of innate immune signaling

About this item

Full title

miR-181a initiates and perpetuates oncogenic transformation through the regulation of innate immune signaling

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2020-06, Vol.11 (1), p.3231-21, Article 3231

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Genomic instability (GI) predisposes cells to malignant transformation, however the molecular mechanisms that allow for the propagation of cells with a high degree of genomic instability remain unclear. Here we report that miR-181a is able to transform fallopian tube secretory epithelial cells through the inhibition of RB1 and stimulator-of-interfe...

Alternative Titles

Full title

miR-181a initiates and perpetuates oncogenic transformation through the regulation of innate immune signaling

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_0767a885d74b4bc6bb838ba3fa5b0523

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0767a885d74b4bc6bb838ba3fa5b0523

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-020-17030-w

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