BMP-2 functional polypeptides relieve osteolysis via bi-regulating bone formation and resorption cou...
BMP-2 functional polypeptides relieve osteolysis via bi-regulating bone formation and resorption coupled with macrophage polarization
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Author / Creator
Wang, Jiaqian , Xue, Yuan , Wang, Yi , Liu, Chang , Hu, Sihan , Zhao, Huan , Gu, Qiaoli , Yang, Huilin , Huang, Lixin , Zhou, Xichao and Shi, Qin
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Osteolysis caused by wear debris around the prosthesis is the main reason for aseptic loosening. Extending prosthetic service life is still challenging. In this study, we first synthesized a bone morphogenetic protein-2 (BMP-2) functional polypeptide (BMP2pp), and evaluated the effects of BMP2pp on macrophage polarization and impaired osteogenesis...
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Full title
BMP-2 functional polypeptides relieve osteolysis via bi-regulating bone formation and resorption coupled with macrophage polarization
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_077341dc732c4264847f7693a8526c08
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_077341dc732c4264847f7693a8526c08
Other Identifiers
ISSN
2057-3995
E-ISSN
2057-3995
DOI
10.1038/s41536-023-00279-2
