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Chronic lithium administration in a mouse model for Krabbe disease

Chronic lithium administration in a mouse model for Krabbe disease

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_077b6b45f2804cfb8869890b840cceb6

Chronic lithium administration in a mouse model for Krabbe disease

About this item

Full title

Chronic lithium administration in a mouse model for Krabbe disease

Publisher

Hoboken, USA: John Wiley & Sons, Inc

Journal title

JIMD Reports, 2022-01, Vol.63 (1), p.50-65

Language

English

Formats

Publication information

Publisher

Hoboken, USA: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Krabbe disease (KD; or globoid cell leukodystrophy) is an autosomal recessive lysosomal storage disorder caused by deficiency of the galactosylceramidase (GALC) enzyme. No cure is currently available for KD. Clinical applied treatments are supportive only. Recently, we demonstrated that two differently acting autophagy inducers (lithium and rapamyc...

Alternative Titles

Full title

Chronic lithium administration in a mouse model for Krabbe disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_077b6b45f2804cfb8869890b840cceb6

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_077b6b45f2804cfb8869890b840cceb6

Other Identifiers

ISSN

2192-8312,2192-8304

E-ISSN

2192-8312

DOI

10.1002/jmd2.12258

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