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Towards an Improvement of Anticancer Activity of Benzyl Adenosine Analogs

Towards an Improvement of Anticancer Activity of Benzyl Adenosine Analogs

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_078b9ea022d94256b3e83b71616844b1

Towards an Improvement of Anticancer Activity of Benzyl Adenosine Analogs

About this item

Full title

Towards an Improvement of Anticancer Activity of Benzyl Adenosine Analogs

Publisher

Switzerland: MDPI AG

Journal title

Molecules (Basel, Switzerland), 2021-11, Vol.26 (23), p.7146

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

N6-Isopentenyladenosine (i6A) is a naturally occurring modified nucleoside displaying in vitro and in vivo antiproliferative and pro-apoptotic properties. In our previous studies, including an in silico inverse virtual screening, NMR experiments and in vitro enzymatic assays, we demonstrated that i6A targeted farnesyl pyrophosphate synthase (FPPS),...

Alternative Titles

Full title

Towards an Improvement of Anticancer Activity of Benzyl Adenosine Analogs

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_078b9ea022d94256b3e83b71616844b1

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_078b9ea022d94256b3e83b71616844b1

Other Identifiers

ISSN

1420-3049

E-ISSN

1420-3049

DOI

10.3390/molecules26237146

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