Profiling genetic mutations in the DNA damage repair genes of oral squamous cell carcinoma patients...
Profiling genetic mutations in the DNA damage repair genes of oral squamous cell carcinoma patients from Pakistan
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Herein, we reported mutations in five DNA Damage Repair (DDR) i.e.,
TP53
,
ATR
,
ATM
,
CHEK1
and
CHEK2
involved in OSCC using NG-WES and their analysis using bioinformatics tools. Out of 42 identified mutations, 16.7% are reported for the 1st time. A total of 28 nonsynonymous SNVs are identified.
TP53
harbored th...
Alternative Titles
Full title
Profiling genetic mutations in the DNA damage repair genes of oral squamous cell carcinoma patients from Pakistan
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_07bfa5f1c04b47e09d702b53be812314
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_07bfa5f1c04b47e09d702b53be812314
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-025-91700-x
