Reconstituting development of pancreatic intraepithelial neoplasia from primary human pancreas duct...
Reconstituting development of pancreatic intraepithelial neoplasia from primary human pancreas duct cells
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Development of systems that reconstitute hallmark features of human pancreatic intraepithelial neoplasia (PanINs), the precursor to pancreatic ductal adenocarcinoma, could generate new strategies for early diagnosis and intervention. However, human cell-based PanIN models with defined mutations are unavailable. Here, we report that genetic modifica...
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Reconstituting development of pancreatic intraepithelial neoplasia from primary human pancreas duct cells
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TN_cdi_doaj_primary_oai_doaj_org_article_07f5f64889bc4267b1acdb73c8a62eac
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_07f5f64889bc4267b1acdb73c8a62eac
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms14686