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Reconstituting development of pancreatic intraepithelial neoplasia from primary human pancreas duct...

Reconstituting development of pancreatic intraepithelial neoplasia from primary human pancreas duct...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_07f5f64889bc4267b1acdb73c8a62eac

Reconstituting development of pancreatic intraepithelial neoplasia from primary human pancreas duct cells

About this item

Full title

Reconstituting development of pancreatic intraepithelial neoplasia from primary human pancreas duct cells

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2017-03, Vol.8 (1), p.14686-14686, Article 14686

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Development of systems that reconstitute hallmark features of human pancreatic intraepithelial neoplasia (PanINs), the precursor to pancreatic ductal adenocarcinoma, could generate new strategies for early diagnosis and intervention. However, human cell-based PanIN models with defined mutations are unavailable. Here, we report that genetic modifica...

Alternative Titles

Full title

Reconstituting development of pancreatic intraepithelial neoplasia from primary human pancreas duct cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_07f5f64889bc4267b1acdb73c8a62eac

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_07f5f64889bc4267b1acdb73c8a62eac

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/ncomms14686

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