Filamentation of the bacterial bi-functional alcohol/aldehyde dehydrogenase AdhE is essential for su...
Filamentation of the bacterial bi-functional alcohol/aldehyde dehydrogenase AdhE is essential for substrate channeling and enzymatic regulation
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Acetaldehyde–alcohol dehydrogenase (AdhE) enzymes are a key metabolic enzyme in bacterial physiology and pathogenicity. They convert acetyl-CoA to ethanol via an acetaldehyde intermediate during ethanol fermentation in an anaerobic environment. This two-step reaction is associated to NAD
+
regeneration, essential for glycolysis. The bifunctio...
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Filamentation of the bacterial bi-functional alcohol/aldehyde dehydrogenase AdhE is essential for substrate channeling and enzymatic regulation
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TN_cdi_doaj_primary_oai_doaj_org_article_07fa1f5397a148c884f80a53704a93fe
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_07fa1f5397a148c884f80a53704a93fe
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2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-15214-y