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Filamentation of the bacterial bi-functional alcohol/aldehyde dehydrogenase AdhE is essential for su...

Filamentation of the bacterial bi-functional alcohol/aldehyde dehydrogenase AdhE is essential for su...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_07fa1f5397a148c884f80a53704a93fe

Filamentation of the bacterial bi-functional alcohol/aldehyde dehydrogenase AdhE is essential for substrate channeling and enzymatic regulation

About this item

Full title

Filamentation of the bacterial bi-functional alcohol/aldehyde dehydrogenase AdhE is essential for substrate channeling and enzymatic regulation

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2020-03, Vol.11 (1), p.1426-1426, Article 1426

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Acetaldehyde–alcohol dehydrogenase (AdhE) enzymes are a key metabolic enzyme in bacterial physiology and pathogenicity. They convert acetyl-CoA to ethanol via an acetaldehyde intermediate during ethanol fermentation in an anaerobic environment. This two-step reaction is associated to NAD
+
regeneration, essential for glycolysis. The bifunctio...

Alternative Titles

Full title

Filamentation of the bacterial bi-functional alcohol/aldehyde dehydrogenase AdhE is essential for substrate channeling and enzymatic regulation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_07fa1f5397a148c884f80a53704a93fe

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_07fa1f5397a148c884f80a53704a93fe

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-020-15214-y

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