BACH1 controls hepatic insulin signaling and glucose homeostasis in mice
BACH1 controls hepatic insulin signaling and glucose homeostasis in mice
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Author / Creator
Jin, Jiayu , He, Yunquan , Guo, Jieyu , Pan, Qi , Wei, Xiangxiang , Xu, Chen , Qi, Zhiyuan , Li, Qinhan , Ma, Siyu , Lin, Jiayi , Jiang, Nan , Ma, Jinghua , Wang, Xinhong , Jiang, Lindi , Ding, Qiurong , Osto, Elena , Zhi, Xiuling and Meng, Dan
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Hepatic insulin resistance is central to the metabolic syndrome. Here we investigate the role of BTB and CNC homology 1 (BACH1) in hepatic insulin signaling. BACH1 is elevated in the hepatocytes of individuals with obesity and patients with non-alcoholic fatty liver disease (NAFLD). Hepatocyte-specific
Bach1
deletion in male mice on a high-fa...
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Full title
BACH1 controls hepatic insulin signaling and glucose homeostasis in mice
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TN_cdi_doaj_primary_oai_doaj_org_article_0808983d7e5640c3b2950fbb7a889718
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0808983d7e5640c3b2950fbb7a889718
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-44088-z
