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Osteoblast-derived vesicles induce a switch from bone-formation to bone-resorption in vivo

Osteoblast-derived vesicles induce a switch from bone-formation to bone-resorption in vivo

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_084b29b141f748d4b865d9342d2c67eb

Osteoblast-derived vesicles induce a switch from bone-formation to bone-resorption in vivo

About this item

Full title

Osteoblast-derived vesicles induce a switch from bone-formation to bone-resorption in vivo

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2022-02, Vol.13 (1), p.1066-1066, Article 1066

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Bone metabolism is regulated by the cooperative activity between bone-forming osteoblasts and bone-resorbing osteoclasts. However, the mechanisms mediating the switch between the osteoblastic and osteoclastic phases have not been fully elucidated. Here, we identify a specific subset of mature osteoblast-derived extracellular vesicles that inhibit b...

Alternative Titles

Full title

Osteoblast-derived vesicles induce a switch from bone-formation to bone-resorption in vivo

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_084b29b141f748d4b865d9342d2c67eb

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_084b29b141f748d4b865d9342d2c67eb

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-022-28673-2

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