SIRT1 promotes lipid metabolism and mitochondrial biogenesis in adipocytes and coordinates adipogene...
SIRT1 promotes lipid metabolism and mitochondrial biogenesis in adipocytes and coordinates adipogenesis by targeting key enzymatic pathways
About this item
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Author / Creator
Majeed, Yasser , Halabi, Najeeb , Madani, Aisha Y. , Engelke, Rudolf , Bhagwat, Aditya M. , Abdesselem, Houari , Agha, Maha V. , Vakayil, Muneera , Courjaret, Raphael , Goswami, Neha , Hamidane, Hisham Ben , Elrayess, Mohamed A. , Rafii, Arash , Graumann, Johannes , Schmidt, Frank and Mazloum, Nayef A.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
The NAD
+
-dependent deacetylase SIRT1 controls key metabolic functions by deacetylating target proteins and strategies that promote SIRT1 function such as SIRT1 overexpression or NAD
+
boosters alleviate metabolic complications. We previously reported that SIRT1-depletion in 3T3-L1 preadipocytes led to C-Myc activation, adipocyte hyper...
Alternative Titles
Full title
SIRT1 promotes lipid metabolism and mitochondrial biogenesis in adipocytes and coordinates adipogenesis by targeting key enzymatic pathways
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_089c9cec17554b53999e1600d089c034
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_089c9cec17554b53999e1600d089c034
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-021-87759-x
