Molecular dynamics simulations of a multicellular model with cell-cell interactions and Hippo signal...
Molecular dynamics simulations of a multicellular model with cell-cell interactions and Hippo signaling pathway
About this item
Full title
Author / Creator
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
The transcriptional coactivator Yes-associated protein (YAP)/transcriptional co-activator with PDZ binding motif (TAZ) induces cell proliferation through nuclear localization at low cell density. Conversely, at extremely high cell density, the Hippo pathway, which regulates YAP/TAZ, is activated. This activation leads to the translocation of YAP/TA...
Alternative Titles
Full title
Molecular dynamics simulations of a multicellular model with cell-cell interactions and Hippo signaling pathway
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_08c80ac2d6974ee78b8f53b9ea7d679d
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_08c80ac2d6974ee78b8f53b9ea7d679d
Other Identifiers
ISSN
1553-7358,1553-734X
E-ISSN
1553-7358
DOI
10.1371/journal.pcbi.1012536