Log in to save to my catalogue

Molecular dynamics simulations of a multicellular model with cell-cell interactions and Hippo signal...

Molecular dynamics simulations of a multicellular model with cell-cell interactions and Hippo signal...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_08c80ac2d6974ee78b8f53b9ea7d679d

Molecular dynamics simulations of a multicellular model with cell-cell interactions and Hippo signaling pathway

About this item

Full title

Molecular dynamics simulations of a multicellular model with cell-cell interactions and Hippo signaling pathway

Publisher

United States: Public Library of Science

Journal title

PLoS computational biology, 2024-11, Vol.20 (11), p.e1012536

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The transcriptional coactivator Yes-associated protein (YAP)/transcriptional co-activator with PDZ binding motif (TAZ) induces cell proliferation through nuclear localization at low cell density. Conversely, at extremely high cell density, the Hippo pathway, which regulates YAP/TAZ, is activated. This activation leads to the translocation of YAP/TA...

Alternative Titles

Full title

Molecular dynamics simulations of a multicellular model with cell-cell interactions and Hippo signaling pathway

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_08c80ac2d6974ee78b8f53b9ea7d679d

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_08c80ac2d6974ee78b8f53b9ea7d679d

Other Identifiers

ISSN

1553-7358,1553-734X

E-ISSN

1553-7358

DOI

10.1371/journal.pcbi.1012536

How to access this item