The case for selection at CCR5-Delta32
The case for selection at CCR5-Delta32
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Publisher
United States: Public Library of Science (PLoS)
Journal title
Language
English
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Publication information
Publisher
United States: Public Library of Science (PLoS)
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Scope and Contents
Contents
The C-C chemokine receptor 5, 32 base-pair deletion (CCR5-Delta32) allele confers strong resistance to infection by the AIDS virus HIV. Previous studies have suggested that CCR5-Delta32 arose within the past 1,000 y and rose to its present high frequency (5%-14%) in Europe as a result of strong positive selection, perhaps by such selective agents a...
Alternative Titles
Full title
The case for selection at CCR5-Delta32
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_08cd36e6040b4450862144729a1f1a28
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_08cd36e6040b4450862144729a1f1a28
Other Identifiers
ISSN
1544-9173
E-ISSN
1545-7885
DOI
10.1371/journal.pbio.0030378
