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A mechanistic modeling platform of SGLT2 inhibition: Implications for type 1 diabetes

A mechanistic modeling platform of SGLT2 inhibition: Implications for type 1 diabetes

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_08d955a3d7174494a0f64eaccfc0dd49

A mechanistic modeling platform of SGLT2 inhibition: Implications for type 1 diabetes

About this item

Full title

A mechanistic modeling platform of SGLT2 inhibition: Implications for type 1 diabetes

Publisher

United States: John Wiley & Sons, Inc

Journal title

CPT: Pharmacometrics & Systems Pharmacology, 2023-06, Vol.12 (6), p.831-841

Language

English

Formats

Publication information

Publisher

United States: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Type 1 diabetes mellitus (T1DM) is an autoimmune disease characterized by abnormally high blood glucose concentrations due to dysfunction of the insulin‐producing beta‐cells in the pancreas. Dapagliflozin, an inhibitor of renal glucose reabsorption, has the potential to improve often suboptimal glycemic control in patients with T1DM through insulin...

Alternative Titles

Full title

A mechanistic modeling platform of SGLT2 inhibition: Implications for type 1 diabetes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_08d955a3d7174494a0f64eaccfc0dd49

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_08d955a3d7174494a0f64eaccfc0dd49

Other Identifiers

ISSN

2163-8306

E-ISSN

2163-8306

DOI

10.1002/psp4.12956

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