Temporal inhibition of autophagy reveals segmental reversal of ageing with increased cancer risk
Temporal inhibition of autophagy reveals segmental reversal of ageing with increased cancer risk
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Author / Creator
Cassidy, Liam D. , Young, Andrew R. J. , Young, Christopher N. J. , Soilleux, Elizabeth J. , Fielder, Edward , Weigand, Bettina M. , Lagnado, Anthony , Brais, Rebecca , Ktistakis, Nicholas T. , Wiggins, Kimberley A. , Pyrillou, Katerina , Clarke, Murray C. H. , Jurk, Diana , Passos, Joao F. and Narita, Masashi
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Autophagy is an important cellular degradation pathway with a central role in metabolism as well as basic quality control, two processes inextricably linked to ageing. A decrease in autophagy is associated with increasing age, yet it is unknown if this is causal in the ageing process, and whether autophagy restoration can counteract these ageing ef...
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Full title
Temporal inhibition of autophagy reveals segmental reversal of ageing with increased cancer risk
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TN_cdi_doaj_primary_oai_doaj_org_article_08d9c43fad6f4fa996ca4382c883b9dc
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_08d9c43fad6f4fa996ca4382c883b9dc
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-14187-x
