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Downregulation of mitochondrial complex I induces ROS production in colorectal cancer subtypes that...

Downregulation of mitochondrial complex I induces ROS production in colorectal cancer subtypes that...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_08da4395fe2b4e27ba67cb17740e7c9b

Downregulation of mitochondrial complex I induces ROS production in colorectal cancer subtypes that differently controls migration

About this item

Full title

Downregulation of mitochondrial complex I induces ROS production in colorectal cancer subtypes that differently controls migration

Publisher

England: BioMed Central Ltd

Journal title

Journal of translational medicine, 2023-08, Vol.21 (1), p.522-522, Article 522

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Colorectal cancer (CRC) can be classified into four molecular subtypes (CMS) among which CMS1 is associated with the best prognosis, while CMS4, the mesenchymal subtype, has the worst outcome. Although mitochondria are considered to be hubs of numerous signaling pathways, the study of mitochondrial metabolism has been neglected for many years. Mito...

Alternative Titles

Full title

Downregulation of mitochondrial complex I induces ROS production in colorectal cancer subtypes that differently controls migration

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_08da4395fe2b4e27ba67cb17740e7c9b

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_08da4395fe2b4e27ba67cb17740e7c9b

Other Identifiers

ISSN

1479-5876

E-ISSN

1479-5876

DOI

10.1186/s12967-023-04341-x

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