T cell-targeting nanoparticles focus delivery of immunotherapy to improve antitumor immunity
T cell-targeting nanoparticles focus delivery of immunotherapy to improve antitumor immunity
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Targeted delivery of compounds to particular cell subsets can enhance therapeutic index by concentrating their action on the cells of interest. Because attempts to target tumors directly have yielded limited benefit, we instead target endogenous immune cell subsets in the circulation that can migrate actively into tumors. We describe antibody-targe...
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Full title
T cell-targeting nanoparticles focus delivery of immunotherapy to improve antitumor immunity
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TN_cdi_doaj_primary_oai_doaj_org_article_08f1cc43b00d4985af2f7a6446427a7e
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_08f1cc43b00d4985af2f7a6446427a7e
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-017-01830-8
