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ABCC6 deficiency promotes dyslipidemia and atherosclerosis

ABCC6 deficiency promotes dyslipidemia and atherosclerosis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_095f67c8ae604bf686f99d9c7ce0ab63

ABCC6 deficiency promotes dyslipidemia and atherosclerosis

About this item

Full title

ABCC6 deficiency promotes dyslipidemia and atherosclerosis

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2021-02, Vol.11 (1), p.3881-3881, Article 3881

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

ABCC6 deficiency promotes ectopic calcification; however, circumstantial evidence suggested that ABCC6 may also influence atherosclerosis. The present study addressed the role of ABCC6 in atherosclerosis using
Ldlr
−/−
mice and pseudoxanthoma elasticum (PXE) patients. Mice lacking the
Abcc6
and
Ldlr
genes were fed an atherogeni...

Alternative Titles

Full title

ABCC6 deficiency promotes dyslipidemia and atherosclerosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_095f67c8ae604bf686f99d9c7ce0ab63

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_095f67c8ae604bf686f99d9c7ce0ab63

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-021-82966-y

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