Post-translational covalent assembly of CAR and synNotch receptors for programmable antigen targetin...
Post-translational covalent assembly of CAR and synNotch receptors for programmable antigen targeting
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Chimeric antigen receptors (CARs) and synthetic Notch (synNotch) receptors are engineered cell-surface receptors that sense a target antigen and respond by activating T cell receptor signaling or a customized gene program, respectively. Here, to expand the targeting capabilities of these receptors, we develop “universal” receptor systems for which...
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Full title
Post-translational covalent assembly of CAR and synNotch receptors for programmable antigen targeting
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TN_cdi_doaj_primary_oai_doaj_org_article_0970abb68a6945a4967176ad1a042aa8
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0970abb68a6945a4967176ad1a042aa8
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-37863-5
