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A new mechanism of consciousness recovery from anesthesia regulated by K+‐Cl– cotransporter KCC2

A new mechanism of consciousness recovery from anesthesia regulated by K+‐Cl– cotransporter KCC2

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0991b9b457d244e0b7309fc55ce2eb8f

A new mechanism of consciousness recovery from anesthesia regulated by K+‐Cl– cotransporter KCC2

About this item

Full title

A new mechanism of consciousness recovery from anesthesia regulated by K+‐Cl– cotransporter KCC2

Author / Creator

Publisher

Denton: John Wiley & Sons, Inc

Journal title

Brain-X, 2023-06, Vol.1 (2), p.n/a

Language

English

Formats

Publication information

Publisher

Denton: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

[...]VPM neurons are disinhibited through GABAA receptor-mediated signaling, which accelerates the recovery of excitability and consciousness arousal. Inhibiting the phosphorylation of the KCC2 Thr1007 site specifically in the VPM brain region of mice under general anesthesia increased the level of KCC2 protein, further prolonging the loss of consc...

Alternative Titles

Full title

A new mechanism of consciousness recovery from anesthesia regulated by K+‐Cl– cotransporter KCC2

Authors, Artists and Contributors

Author / Creator

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_0991b9b457d244e0b7309fc55ce2eb8f

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0991b9b457d244e0b7309fc55ce2eb8f

Other Identifiers

ISSN

2835-3153

E-ISSN

2835-3153

DOI

10.1002/brx2.19

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