A new mechanism of consciousness recovery from anesthesia regulated by K+‐Cl– cotransporter KCC2
A new mechanism of consciousness recovery from anesthesia regulated by K+‐Cl– cotransporter KCC2
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Denton: John Wiley & Sons, Inc
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English
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Denton: John Wiley & Sons, Inc
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[...]VPM neurons are disinhibited through GABAA receptor-mediated signaling, which accelerates the recovery of excitability and consciousness arousal. Inhibiting the phosphorylation of the KCC2 Thr1007 site specifically in the VPM brain region of mice under general anesthesia increased the level of KCC2 protein, further prolonging the loss of consc...
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A new mechanism of consciousness recovery from anesthesia regulated by K+‐Cl– cotransporter KCC2
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TN_cdi_doaj_primary_oai_doaj_org_article_0991b9b457d244e0b7309fc55ce2eb8f
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0991b9b457d244e0b7309fc55ce2eb8f
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ISSN
2835-3153
E-ISSN
2835-3153
DOI
10.1002/brx2.19