Targeted Inhibition of Matrix Metalloproteinase-8 Prevents Aortic Dissection in a Murine Model
Targeted Inhibition of Matrix Metalloproteinase-8 Prevents Aortic Dissection in a Murine Model
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Author / Creator
Zhang, Chengxin , Niu, Kaiyuan , Ren, Meixia , Zhou, Xinmiao , Yang, Zhisheng , Yang, Mei , Wang, Xinxin , Luo, Jun , Shao, Yue , Zhang, Cheng , Chen, Dan , Gao, Shan , Ge, Shenglin , Wu, Qingchen and Xiao, Qingzhong
Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Contents
Aortic dissection (AD) is a lethal aortic pathology without effective medical treatments since the underlying pathological mechanisms responsible for AD remain elusive. Matrix metalloproteinase-8 (MMP8) has been previously identified as a key player in atherosclerosis and arterial remodeling. However, the functional role of MMP8 in AD remains large...
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Full title
Targeted Inhibition of Matrix Metalloproteinase-8 Prevents Aortic Dissection in a Murine Model
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TN_cdi_doaj_primary_oai_doaj_org_article_09beafbff41d4a389d65577d5a09f254
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_09beafbff41d4a389d65577d5a09f254
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ISSN
2073-4409
E-ISSN
2073-4409
DOI
10.3390/cells11203218
