CYLD regulates cell ferroptosis through Hippo/YAP signaling in prostate cancer progression
CYLD regulates cell ferroptosis through Hippo/YAP signaling in prostate cancer progression
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Author / Creator
Gu, Yanan , Wu, Shiqi , Fan, Junjie , Meng, Zeji , Gao, Guoqiang , Liu, Tianjie , Wang, Qi , Xia, Huayu , Wang, Xinyang and Wu, Kaijie
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Prostate cancer (PCa) is one of the most common malignancy in men. However, the molecular mechanism of its pathogenesis has not yet been elucidated. In this study, we demonstrated that CYLD, a novel deubiquitinating enzyme, impeded PCa development and progression via tumor suppression. First, we found that CYLD was downregulated in PCa tissues, and...
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Full title
CYLD regulates cell ferroptosis through Hippo/YAP signaling in prostate cancer progression
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TN_cdi_doaj_primary_oai_doaj_org_article_09c50d7e5f4a495b9ad3c8087e1b337c
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_09c50d7e5f4a495b9ad3c8087e1b337c
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ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-024-06464-5