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Functional nanozyme system for synergistic tumor immunotherapy via cuproptosis and ferroptosis activ...

Functional nanozyme system for synergistic tumor immunotherapy via cuproptosis and ferroptosis activ...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_09eddc6cc8284c55ad7bac3919b81d0f

Functional nanozyme system for synergistic tumor immunotherapy via cuproptosis and ferroptosis activation

About this item

Full title

Functional nanozyme system for synergistic tumor immunotherapy via cuproptosis and ferroptosis activation

Publisher

England: BioMed Central Ltd

Journal title

Journal of nanobiotechnology, 2025-03, Vol.23 (1), p.212-20, Article 212

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Elevated copper levels induce tumor cuproptosis and ferroptosis, leading to immunogenic cell death and subsequent antitumor immune responses. However, dysregulated copper metabolism in tumor cells maintains homeostatic copper balance, while hypoxic microenvironments hinder therapeutic efficacy. In this study, we present a nanozyme system, termed Cu...

Alternative Titles

Full title

Functional nanozyme system for synergistic tumor immunotherapy via cuproptosis and ferroptosis activation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_09eddc6cc8284c55ad7bac3919b81d0f

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_09eddc6cc8284c55ad7bac3919b81d0f

Other Identifiers

ISSN

1477-3155

E-ISSN

1477-3155

DOI

10.1186/s12951-025-03284-3

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