Modulation of oxidative and nitrosative stress attenuates microvascular hyperpermeability in ovine m...
Modulation of oxidative and nitrosative stress attenuates microvascular hyperpermeability in ovine model of Pseudomonas aeruginosa sepsis
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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In sepsis, microvascular hyperpermeability caused by oxidative/nitrosative stress (O&NS) plays an important role in tissue edema leading to multi-organ dysfunctions and increased mortality. We hypothesized that a novel compound R-107, a modulator of O&NS, effectively ameliorates the severity of microvascular hyperpermeability and preserves multi-or...
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Modulation of oxidative and nitrosative stress attenuates microvascular hyperpermeability in ovine model of Pseudomonas aeruginosa sepsis
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TN_cdi_doaj_primary_oai_doaj_org_article_0a205f198d544ea58822c974d20c9099
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0a205f198d544ea58822c974d20c9099
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-021-03320-w
