CREB3 gain of function variants protect against ALS
CREB3 gain of function variants protect against ALS
About this item
Full title
Author / Creator
Megat, Salim , Marques, Christine , Hernán-Godoy, Marina , Sellier, Chantal , Stuart-Lopez, Geoffrey , Dirrig-Grosch, Sylvie , Gorin, Charlotte , Brunet, Aurore , Fischer, Mathieu , Keime, Céline , Kessler, Pascal , Mendoza-Parra, Marco Antonio , Zwamborn, Ramona A. J. , Veldink, Jan H. , Scholz, Sonja W. , Ferrucci, Luigi , Ludolph, Albert , Traynor, Bryan , Chio, Adriano , Dupuis, Luc and Rouaux, Caroline
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Amyotrophic lateral sclerosis (ALS) is a fatal and rapidly evolving neurodegenerative disease arising from the loss of glutamatergic corticospinal neurons (CSN) and cholinergic motoneurons (MN). Here, we performed comparative cross-species transcriptomics of CSN using published snRNA-seq data from the motor cortex of ALS and control postmortem tiss...
Alternative Titles
Full title
CREB3 gain of function variants protect against ALS
Authors, Artists and Contributors
Author / Creator
Marques, Christine
Hernán-Godoy, Marina
Sellier, Chantal
Stuart-Lopez, Geoffrey
Dirrig-Grosch, Sylvie
Gorin, Charlotte
Brunet, Aurore
Fischer, Mathieu
Keime, Céline
Kessler, Pascal
Mendoza-Parra, Marco Antonio
Zwamborn, Ramona A. J.
Veldink, Jan H.
Scholz, Sonja W.
Ferrucci, Luigi
Ludolph, Albert
Traynor, Bryan
Chio, Adriano
Dupuis, Luc
Rouaux, Caroline
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_0a55d58b8fd342a4a32ca5f5bc01b909
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0a55d58b8fd342a4a32ca5f5bc01b909
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-025-58098-6
