STAT3/LINC00671 axis regulates papillary thyroid tumor growth and metastasis via LDHA-mediated glyco...
STAT3/LINC00671 axis regulates papillary thyroid tumor growth and metastasis via LDHA-mediated glycolysis
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Author / Creator
Huo, Nan , Cong, Rui , Sun, Zhi-jia , Li, Wen-chao , Zhu, Xiang , Xue, Chun-yuan , Chen, Zhao , Ma, Lu-yuan , Chu, Zhong , Han, Yu-chen , Kang, Xiao-feng , Jia, Song-hao , Du, Nan , Kang, Lei and Xu, Xiao-jie
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Lactate dehydrogenase A (LDHA), a critical component of the glycolytic pathway, relates to the development of various cancers, including thyroid cancer. However, the regulatory mechanism of LDHA inhibition and the physiological significance of the LDHA inhibitors in papillary thyroid cancer (PTC) are unknown. Long non-coding RNA (lncRNA) plays a vi...
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Full title
STAT3/LINC00671 axis regulates papillary thyroid tumor growth and metastasis via LDHA-mediated glycolysis
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TN_cdi_doaj_primary_oai_doaj_org_article_0a55de72db7b48a4b5078d40f4b7ae14
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0a55de72db7b48a4b5078d40f4b7ae14
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ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-021-04081-0